Pressure-induced oxidative activation of PKG enables vasoregulation by Ca 2+ sparks and BK channels-Reference-Cited by-同舟云学术

Pressure-induced oxidative activation of PKG enables vasoregulation by Ca 2+ sparks and BK channels

Published:2016-10-11 Issue:449 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Khavandi Kaivan¹²,Baylie Rachael L.¹,Sugden Sarah A.¹,Ahmed Majid¹³,Csato Viktoria¹⁴,Eaton Philip²,Hill-Eubanks David C.³,Bonev Adrian D.³,Nelson Mark T.¹³,Greenstein Adam S.¹

Affiliation:

1. Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Sciences Center, Manchester M13 9NT, U.K.

2. King’s College London, Cardiovascular Division, British Heart Foundation Centre of Excellence, Rayne Institute, St Thomas’ Hospital, London SE1 7EH, U.K.

3. Department of Pharmacology, University of Vermont, Burlington, VT 05405-0068, USA.

4. Division of Clinical Physiology, Institute of Cardiology, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen 4012, Hungary.

Abstract

Constriction of small-diameter arteries triggers a signaling pathway that causes their dilation.

Funder

NIH

Totman Medical Research Trust

Horizon 2020

Fondation Leducq

British Heart Foundation

Medical Research Council

European Research Council

National Institute for Health Research Comprehensive Biomedical Research Centre

Publisher