Cripto Localizes Nodal at the Limiting Membrane of Early Endosomes-Reference-Cited by-同舟云学术

Cripto Localizes Nodal at the Limiting Membrane of Early Endosomes

Published:2008-11-11 Issue:45 Volume:1 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Blanchet Marie-Hélène¹,Le Good J. Ann¹,Oorschot Viola²,Baflast Stéphane¹,Minchiotti Gabriella³,Klumperman Judith²,Constam Daniel B.¹

Affiliation:

1. Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Chemin des Boveresses 155, CH 1066 Epalinges, Switzerland.

2. Cell Microscopy Center and Department of Cell Biology, University Medical Centre Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.

3. Institute of Genetics and Biophysics “A. Buzzati-Traverso,” Via P. Castellino 111, 80131 Naples, Italy.

Abstract

Cripto facilitates ALK4 signaling by attenuating intraendosomal sorting of internalized Nodal.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference48 articles.

1. Molecular characterization of a gene of the ‘EGF family’ expressed in undifferentiated human NTERA2 teratocarcinoma cells.

2. Nodal and Cripto-1: Embryonic Pattern Formation Genes Involved in Mammary Gland Development and Tumorigenesis

3. Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

4. Overexpression of Human Cripto-1 in Transgenic Mice Delays Mammary Gland Development and Differentiation and Induces Mammary Tumorigenesis

5. Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo

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