T Cell Receptor–Dependent Activation of mTOR Signaling in T Cells Is Mediated by Carma1 and MALT1, But Not Bcl10-Reference-Cited by-同舟云学术

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T Cell Receptor–Dependent Activation of mTOR Signaling in T Cells Is Mediated by Carma1 and MALT1, But Not Bcl10

Published:2014-06-10 Issue:329 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Hamilton Kristia S.¹²,Phong Binh¹²,Corey Catherine³,Cheng Jing¹,Gorentla Balachandra⁴,Zhong Xiaoping⁴,Shiva Sruti³,Kane Lawrence P.¹

Affiliation:

1. Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

2. Graduate Program in Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

3. Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

4. Departments of Pediatrics and Immunology, Duke University Medical Center, Durham, NC 27710, USA.

Abstract

By shifting the constituents of signalosomes, T cells may stimulate distinct pathways in response to antigens.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference66 articles.

1. Growing roles for the mTOR pathway

2. mTOR Signaling in Growth Control and Disease

3. TOR Signaling in Growth and Metabolism

4. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size

5. Phosphoinositide 3-Kinases and Leukocyte Migration

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