Translational control by lysine-encoding A-rich sequences

Author:

Arthur Laura L.1,Pavlovic-Djuranovic Slavica1,Koutmou Kristin S.2,Green Rachel23,Szczesny Pawel4,Djuranovic Sergej1

Affiliation:

1. Department of Cell Biology and Physiology, Washington University School of Medicine, 600 South Euclid Avenue, Campus Box 8228, St. Louis, MO 63110, USA.

2. Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

3. Howard Hughes Medical Institute.

4. Department of Bioinformatics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.

Abstract

Conserved poly(A) tracks in coding regions are attenuators of translation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

1. 22 Regulation of Termination and Recoding;Dinman J. D.;Cold Spring Harb. Monogr. Arch.,2007

2. Principles of translational control: An overview;Hershey J. W.;Cold Spring Harb. Perspect. Biol.,2012

3. Translation drives mRNA quality control;Shoemaker C. J.;Nat. Struct. Mol. Biol.,2012

4. Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation;Doma M. K.;Nature,2006

5. Control of translation efficiency in yeast by codon–anticodon interactions;Letzring D. P.;RNA,2010

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