Tunable and label-free virus enrichment for ultrasensitive virus detection using carbon nanotube arrays

Author:

Yeh Yin-Ting12ORCID,Tang Yi3,Sebastian Aswathy4,Dasgupta Archi5,Perea-Lopez Nestor6,Albert Istvan47,Lu Huaguang3,Terrones Mauricio25678,Zheng Si-Yang1279

Affiliation:

1. Micro and Nano Integrated Biosystem Laboratory, Department of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA.

2. Penn State Material Research Institute, Pennsylvania State University, University Park, PA 16802, USA.

3. Department of Veterinary and Biomedical Science, Pennsylvania State University, University Park, PA 16802, USA.

4. Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.

5. Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.

6. Department of Physics and Center for 2-Dimensional and Layered Materials, Pennsylvania State University, University Park, PA 16802, USA.

7. Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.

8. Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802, USA.

9. Department of Electrical Engineering, Pennsylvania State University, University Park, PA 16802, USA.

Abstract

Aligned carbon nanotube–integrated device can effectively trap and enrich viruses from field samples without using antibodies.

Funder

National Center for Advancing Translational Sciences

National Institutes of Health

Air Force Office of Scientific Research

Pennsylvania State University

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference85 articles.

1. The Perpetual Challenge of Infectious Diseases

2. U.S. Department of Agriculture Update on the Highly-Pathogenic Avian Influenza Outbreak of 2014–2015.

3. A Strategy To Estimate Unknown Viral Diversity in Mammals

4. Human viruses: discovery and emergence

5. Viral pathogen discovery

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