Molecular Determinants of State-Dependent Block of Na + Channels by Local Anesthetics
Author:
Affiliation:
1. Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference47 articles.
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2. A rat brain na+ channel α subunit with novel gating properties
3. AULD, V.J., A NEUTRAL AMINO-ACID CHANGE IN SEGMENT-IIS4 DRAMATICALLY ALTERS THE GATING PROPERTIES OF THE VOLTAGE-DEPENDENT SODIUM-CHANNEL, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87: 323 (1990).
4. BACKX, P.H., MOLECULAR LOCALIZATION OF AN ION-BINDING SITE WITHIN THE PORE OF MAMMALIAN SODIUM-CHANNELS, SCIENCE 257: 248 (1992).
5. BEAN, B.P., LIDOCAINE BLOCK OF CARDIAC SODIUM-CHANNELS, JOURNAL OF GENERAL PHYSIOLOGY 81: 613 (1983).
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