Looking at neurodevelopment through a big data lens-Reference-Cited by-同舟云学术

Looking at neurodevelopment through a big data lens

Published:2020-09-18 Issue:6510 Volume:369 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Briscoe James¹^ORCID,Marín Oscar²³^ORCID

Affiliation:

1. The Francis Crick Institute, London NW1 1AT, UK.

2. Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London SE1 1UL, UK.

3. MRC Centre for Neurodevelopmental Disorders, King’s College London, London SE1 1UL, UK.

Abstract

Insights from big data The billions of neurons that make up the adult brain are organized into domains and circuits during development. High-resolution measurements such as those enabled by single-cell molecular profiling have revealed unexpected cellular diversity. Genomic tools are lending insight into mechanisms behind neurodevelopmental disorders. Briscoe and Marèn review the insights gained as big data analyses are applied to neurodevelopmental questions. Science , this issue p. eaaz8627

Funder

European Research Council

The Wellcome Trust

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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