Assembly of a nucleus-like structure during viral replication in bacteria-Reference-Cited by-同舟云学术

Assembly of a nucleus-like structure during viral replication in bacteria

Published:2017-01-13 Issue:6321 Volume:355 Page:194-197
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Chaikeeratisak Vorrapon¹,Nguyen Katrina¹,Khanna Kanika¹,Brilot Axel F.²,Erb Marcella L.¹,Coker Joanna K. C.¹,Vavilina Anastasia¹,Newton Gerald L.¹,Buschauer Robert³,Pogliano Kit¹,Villa Elizabeth³,Agard David A.²,Pogliano Joe¹

Affiliation:

1. Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.

2. Howard Hughes Medical Institute (HHMI) and the Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.

3. Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA.

Abstract

Phages build themselves a wall The compartmentalization of DNA replication away from other cytoplasmic events is a key feature of the cell nucleus. Chaikeeratisak et al. studied the replication of the very large Pseudomonas bacteriophage 201φ2-1 by using fluorescence microscopy and cryo–electron tomography. They found that the phage assembled a nucleus-like compartment when it infected a bacterial cell. The phage genome was completely enclosed by an apparently contiguous protein shell, within which DNA replication, recombination, and transcription occurred. Translation, precursor biosynthesis, and viral assembly occurred outside the structure. Science , this issue p. 194

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference20 articles.

1. Viruses and cells intertwined since the dawn of evolution

2. Improved isolation of undersampled bacteriophages: finding of distant terminase genes

3. Characterization of Pseudomonas chlororaphis myovirus 201ϕ2-1 via genomic sequencing, mass spectrometry, and electron microscopy

4. A Phage Tubulin Assembles Dynamic Filaments by an Atypical Mechanism to Center Viral DNA within the Host Cell

5. A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells

Cited by 218 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A game of resistance: War between bacteria and phages and how phage cocktails can be the solution;Virology;2024-11

2. Genomic transfer via membrane vesicle: a strategy of giant phage phiKZ for early infection;Journal of Virology;2024-09-11

3. Structure of the Bacteriophage PhiKZ Non-virion RNA Polymerase Transcribing from its Promoter p119L;Journal of Molecular Biology;2024-09

4. Capsid structure of bacteriophage ΦKZ provides insights into assembly and stabilization of jumbo phages;Nature Communications;2024-08-02

5. A Cool Look at Positive-Strand RNA Virus Replication Organelles: New Insights from Cryo–Electron Microscopy;Annual Review of Biochemistry;2024-08-02