<i>N</i> ′-Nitrosonornicotine in Tobacco-Reference-Cited by-同舟云学术

N ′-Nitrosonornicotine in Tobacco

Published:1974-10-18 Issue:4160 Volume:186 Page:265-267
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Hoffmann Dietrich¹,Hecht Stephen S.¹,Ornaf Raphael M.¹,Wynder Ernst L.¹

Affiliation:

1. Divisions of Environmental Carcinogenesis and Epidemiology, Naylor Dana Institute for Disease Prevention, American Health Foundation, New York 10021

Abstract

N ′-Nitrosonornicotine, a potential carcinogen, has been positively identified in unburned tobacco. The amount in commercial U.S. tobacco products is between 1.9 to 88.6 parts per million, one of the highest values of an environmental nitrosamine yet reported. The amount in food and drink rarely exceeds 0.1 part per million. This compound is the first example of a potential organic carcinogen isolated from tobacco.

Publisher

American Association for the Advancement of Science (AAAS)

Link

https://www.science.org/doi/pdf/10.1126/science.186.4160.265

Reference30 articles.

1. Health Services and' Mental Health Administration Publication 73-8704 (1973).

2. Royal College of Physicians Smoking and Health (1962).

3. Royal College of Physicians Smoking and Health Now (1971).

4. U.S. Public Health Report 1103 (1964).

5. BOCK, F.G., NATURE OF TUMOR-PROMOTING AGENTS IN TOBACCO PRODUCTS, CANCER RESEARCH 28: 2363 (1968).

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