Decoding motor imagery from the posterior parietal cortex of a tetraplegic human

Author:

Aflalo Tyson1,Kellis Spencer1,Klaes Christian1,Lee Brian2,Shi Ying1,Pejsa Kelsie1,Shanfield Kathleen3,Hayes-Jackson Stephanie3,Aisen Mindy3,Heck Christi2,Liu Charles2,Andersen Richard A.1

Affiliation:

1. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

2. USC Neurorestoration Center and the Departments of Neurosurgery and Neurology, University of Southern California, Los Angeles, CA 90033, USA.

3. Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA.

Abstract

Brain imagination to control external devices Studies in monkeys have implicated the brain's posterior parietal cortex in high-level coding of planned and imagined actions. Aflalo et al. implanted two microelectrode arrays in the posterior parietal cortex of a tetraplegic patient (see the Perspective by Pruszynski and Diedrichsen). They asked the patient to imagine various types of limb or eye movements. As predicted, motor imagery involved the same types of neural population activity involved in actual movements, which could potentially be exploited in prosthetic limb control. Science , this issue p. 906 ; see also p. 860

Funder

NIH

University of Southern California

Boswell Foundation

Defense Department

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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