Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair-Reference-Cited by-同舟云学术

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

Published:2012-07-20 Issue:6092 Volume:337 Page:358-362
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Tsai Hui-Hsin¹²³,Li Huiliang⁴,Fuentealba Luis C.⁵³,Molofsky Anna V.¹⁶³,Taveira-Marques Raquel⁴,Zhuang Helin⁴,Tenney April¹²,Murnen Alice T.¹²³,Fancy Stephen P. J.¹²³,Merkle Florian⁵,Kessaris Nicoletta⁴,Alvarez-Buylla Arturo⁵³,Richardson William D.⁴,Rowitch David H.¹²⁵³

Affiliation:

1. Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA 94143, USA.

2. Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA.

3. Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA 94143, USA.

4. Wolfson Institute for Biomedical Research and Research Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.

5. Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143, USA.

6. Department of Psychiatry/Langley-Porter Institute, University of California San Francisco, San Francisco, CA 94143, USA.

Abstract

Born to Stay Together For as many neurons as there are in the brain, there are many more astrocytes. These backstage workers perform a variety of functions, such as sustaining the blood-brain barrier and providing a stabilized environment for neurons. Diversity of astrocyte function is reflected in different molecular expression profiles. Tsai et al. (p. 358 , published online 28 June) selectively labeled astrocytes that originated from different domains of the mouse spinal cord and found that not all astrocytes are created equal: Neighborhoods of astrocytes were defined by shared birthplaces.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference42 articles.

1. H. Kettenmann B. R. Ransom Neuroglia (Oxford Univ. Press Oxford 2005).

2. The astrocyte odyssey;Wang D. D.;Prog. Neurobiol.,2008

3. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

4. Gap Junction-Mediated Astrocytic Networks in the Mouse Barrel Cortex

5. Motor Behavior Activates Bergmann Glial Networks

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