Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus-Reference-Cited by-同舟云学术

Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus

Published:2015-05 Issue:6234 Volume:348 Page:574-578
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Zhou Xiaoxue¹²³,Halladin David K.²³⁴,Rojas Enrique R.²³⁵,Koslover Elena F.²³,Lee Timothy K.⁵,Huang Kerwyn Casey⁴⁵,Theriot Julie A.²³⁴

Affiliation:

1. Department of Chemistry, Stanford University, Stanford, CA 94305, USA.

2. Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. Howard Hughes Medical Institute (HHMI), Stanford University School of Medicine, Stanford, CA 94305, USA.

4. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

5. Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.

Abstract

Pop goes the coccus Daughter cell separation in Staphylococcus aureus proceeds much like the cracking of an egg. So say Zhou et al. , who examined dividing cells with millisecond precision using high-speed videomicroscopy. Rather than proceeding gradually, tiny imperfections in the mother cell wall were seen to crack open, leaving two daughter cells linked by a hinge. Science , this issue p. 574

Funder

NIH

HHMI

National Institute of Allergy and Infectious Diseases

James S. McDonnell Foundation

Stanford Cell and Molecular Biology Training Grant

NIH Center for Biomedical Computation

Stanford Center for Systems Biology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary