The Science of Resilience: Implications for the Prevention and Treatment of Depression-Reference-Cited by-全球学者库

The Science of Resilience: Implications for the Prevention and Treatment of Depression

Published:2012-10-05 Issue:6103 Volume:338 Page:79-82
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Southwick Steven M.¹,Charney Dennis S.²

Affiliation:

1. Yale University School of Medicine and Yale Child Study Center, U.S. Department of Veterans Affairs (VA) National Center for Post-Traumatic Stress Disorder, VA Connecticut Healthcare System, 950 Campbell Avenue 116A, West Haven, CT 06516, USA.

2. Mount Sinai School of Medicine, The Mount Sinai Medical Center, Department of Psychiatry, Department of Neuroscience, and Department of Pharmacology and Systems Therapeutics, One Gustave L. Levy Place, Box 1217, New York, NY 10029, USA.

Abstract

Human responses to stress and trauma vary widely. Some people develop trauma-related psychological disorders, such as posttraumatic stress disorder (PTSD) and depression; others develop mild to moderate psychological symptoms that resolve rapidly; still others report no new psychological symptoms in response to traumatic stress. Individual variability in how animals and humans respond to stress and trauma depends on numerous genetic, developmental, cognitive, psychological, and neurobiological risk and protective factors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

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4. Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

5. The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

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