Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China-Reference-Cited by-全球学者库

Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China

Published:2003-10-10 Issue:5643 Volume:302 Page:276-278
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Guan Y.¹²³⁴,Zheng B. J.¹²³⁴,He Y. Q.¹²³⁴,Liu X. L.¹²³⁴,Zhuang Z. X.¹²³⁴,Cheung C. L.¹²³⁴,Luo S. W.¹²³⁴,Li P. H.¹²³⁴,Zhang L. J.¹²³⁴,Guan Y. J.¹²³⁴,Butt K. M.¹²³⁴,Wong K. L.¹²³⁴,Chan K. W.¹²³⁴,Lim W.¹²³⁴,Shortridge K. F.¹²³⁴,Yuen K. Y.¹²³⁴,Peiris J. S. M.¹²³⁴,Poon L. L. M.¹²³⁴

Affiliation:

1. Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong Special Administrative Region (S.A.R.), of the People's Republic of China (China).

2. Center for Disease Control and Prevention, Shenzhen, Guangdong Province, China.

3. Department of Pathology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong S.A.R., China.

4. Government Virus Unit, Department of Health, Hong Kong S.A.R., China.

Abstract

A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides ) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference12 articles.

1. World Health Organization (WHO) (www.who.int/csr/sars/en/).

2. WHO Cumulative Number of Reported Probable Cases of Severe Acute Respiratory Syndrome (SARS) (www.who.int/csr/sars/country/2003_05_20/en/).

3. Coronavirus as a possible cause of severe acute respiratory syndrome

4. A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

5. Koch's postulates fulfilled for SARS virus

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