A genome-wide transcriptomic analysis of protein-coding genes in human blood cells-Reference-Cited by-同舟云学术

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Published:2019-12-20 Issue:6472 Volume:366 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Uhlen Mathias¹²³^ORCID,Karlsson Max J.¹^ORCID,Zhong Wen¹^ORCID,Tebani Abdellah¹^ORCID,Pou Christian⁴^ORCID,Mikes Jaromir⁴^ORCID,Lakshmikanth Tadepally⁴^ORCID,Forsström Björn¹^ORCID,Edfors Fredrik¹^ORCID,Odeberg Jacob¹⁵^ORCID,Mardinoglu Adil¹⁶^ORCID,Zhang Cheng¹^ORCID,von Feilitzen Kalle¹^ORCID,Mulder Jan²^ORCID,Sjöstedt Evelina²^ORCID,Hober Andreas¹^ORCID,Oksvold Per¹^ORCID,Zwahlen Martin¹^ORCID,Ponten Fredrik⁷^ORCID,Lindskog Cecilia⁷^ORCID,Sivertsson Åsa¹^ORCID,Fagerberg Linn¹^ORCID,Brodin Petter⁴⁸

Affiliation:

1. Science for Life Laboratory, KTH–Royal Institute of Technology, Stockholm, Sweden.

2. Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

3. Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark.

4. Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden.

5. Coagulation Unit, Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.

6. Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, UK.

7. Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

8. Unit of Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden.

Abstract

A blood cell protein-expression atlas Genome-wide analyses are increasingly providing resources for advances in basic and applied biomedical science. Uhlen et al. performed a global expression analysis of human blood cell types and integrated this data with data across all major human tissues and organs in the human protein atlas. This comprehensive compendium allows for classification of all human protein-coding genes with regard to their tissue- and cell-type distribution. Science , this issue p. eaax9198

Funder

Familjen Erling-Perssons Stiftelse

Knut och Alice Wallenbergs Stiftelse

Novo Nordisk Fonden

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference61 articles.

1. The Human Cell Atlas

2. The NIH Common Fund Human Biomolecular Atlas Program (HuBMAP): Building a Framework for Mapping the Human Body

3. Chan Zuckerberg Biohub funds first crop of 47 investigators