Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms-Reference-Cited by-同舟云学术

Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms

Published:2012-07-13 Issue:6091 Volume:337 Page:236-239
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Berk Veysel¹²,Fong Jiunn C. N.³,Dempsey Graham T.⁴,Develioglu Omer N.⁵,Zhuang Xiaowei⁴⁶,Liphardt Jan¹²⁷,Yildiz Fitnat H.³,Chu Steven⁸

Affiliation:

1. Department of Physics, University of California, Berkeley, CA 94720, USA.

2. Molecular and Cellular Biology, University of California, Berkeley, CA 94720, USA.

3. Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064, USA.

4. Biophysics Program, Harvard University, Cambridge, MA 02138, USA.

5. Department of Otorhinolaryngology, Taksim Training and Research Hospital, Istanbul, Turkey.

6. Department of Chemistry and Chemical Biology, Department of Physics, and Howard Hughes Medical Institute (HHMI), Harvard University, Cambridge, MA 02138, USA.

7. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

8. U.S. Department of Energy, 1000 Independence Avenue, SW, Washington, DC 20585, USA.

Abstract

Biofilms Up Close Many bacterial infections involve biofilm formation. Cells within a biofilm are significantly more resistant to immune clearance and antibiotics compared to unattached, planktonic cells. Berk et al. (p. 236 ) applied superresolution optical methods to image living bacteria with nanometer-scale precision as they form a biofilm. Vibrio cholerae biofilms were observed to have three distinct levels of spatial organization: cells, clusters of cells, and collections of clusters. Each cell cluster was wrapped in a flexible, elastic envelope. Several V. cholerae matrix proteins played complementary architectural roles during biofilm development. RbmA provided cell-cell adhesion, Bap1 allowed the developing biofilm to adhere to surfaces, and heterogeneous mixtures of VPS, RbmC, and Bap1 formed the dynamic, flexible, and ordered envelopes that encase the cell clusters.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

1. Bacterial Biofilms: A Common Cause of Persistent Infections

2. Biofilm formation and dispersal and the transmission of human pathogens

3. Bacterial Biofilms: An Emerging Link to Disease Pathogenesis

4. Antibiotic resistance of bacteria in biofilms

5. A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance

Cited by 328 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Outer membrane vesicles and the outer membrane protein OmpU govern Vibrio cholerae biofilm matrix assembly;mBio;2024-01-11

2. Marine BacteriaAlteromonasspp. Require UDP-glucose-4-epimerase for Aggregation and Production of Sticky Exopolymer;2024-01-11

3. Elevated concentrations of polymyxin B elicit a biofilm-specific resistance mechanism in Vibrio cholerae;Research in Microbiology;2024-01

4. DNase-mimetics based on bimetallic hierarchically macroporous MOFs for the efficient inhibition of bacterial biofilm;Science China Materials;2023-12-26

5. Biofilms Communities In The Soil: Characteristic And Interactions Using Mathematical Model;Research in Microbiology;2023-11