Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

Author:

Park Sang-Youl1,Fung Pauline2,Nishimura Noriyuki3,Jensen Davin R.4,Fujii Hiroaki1,Zhao Yang2,Lumba Shelley2,Santiago Julia5,Rodrigues Americo5,Chow Tsz-fung F.2,Alfred Simon E.2,Bonetta Dario6,Finkelstein Ruth7,Provart Nicholas J.28,Desveaux Darrell28,Rodriguez Pedro L.5,McCourt Peter2,Zhu Jian-Kang1,Schroeder Julian I.3,Volkman Brian F.4,Cutler Sean R.191011

Affiliation:

1. Department of Botany and Plant Sciences, University of California at Riverside, Riverside, CA 92521, USA.

2. Department of Cell and Systems Biology, University of Toronto, 25 Willcocks Street, Toronto, ON, M5S 3B2, Canada.

3. Division of Biological Sciences, Cell and Developmental Biology Section, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

4. Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

5. Instituto de Biología Molecular y Celular de Plantas, Universidad Politécnica de Valencia, Avenida de los Naranjos, Edificio CPI, 8E, ES-46022 Valencia, Spain.

6. Faculty of Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, ON, L1H 7K4, Canada.

7. Department of Molecular, Cellular, and Developmental Biology, University of California at Santa Barbara, Santa Barbara, CA 93106, USA.

8. Centre for the Analysis of Genome Evolution and Function, University of Toronto, 25 Willcocks Street, Toronto, ON, M5S 3B2, Canada.

9. Center for Plant Cell Biology, University of California at Riverside, Riverside, CA 92521, USA.

10. Institute for Genome Biology, University of California at Riverside, Riverside, CA 92521, USA.

11. Department of Chemistry, University of California at Riverside, Riverside, CA 92521, USA.

Abstract

ABA Receptor Rumbled? The plant hormone abscisic acid (ABA) is critical for normal development and for mediating plant responses to stressful environmental conditions. Now, two papers present analyses of candidate ABA receptors (see the news story by Pennisi ). Ma et al. (p. 1064; published online 30 April) and Park et al. (p. 1068, published online 30 April) used independent strategies to search for proteins that physically interact with ABI family phosphatase components of the ABA response signaling pathway. Both groups identified different members of the same family of proteins, which appear to interact with ABI proteins to form a heterocomplex that can act as the ABA receptor. The variety of both families suggests that the ABA receptor may not be one entity, but rather a class of closely related complexes, which may explain previous difficulties in establishing its identity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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