Ancient DNA indicates human population shifts and admixture in northern and southern China

Author:

Yang Melinda A.123ORCID,Fan Xuechun45,Sun Bo6,Chen Chungyu7,Lang Jianfeng8,Ko Ying-Chin9,Tsang Cheng-hwa10ORCID,Chiu Hunglin10ORCID,Wang Tianyi1211ORCID,Bao Qingchuan12,Wu Xiaohong13ORCID,Hajdinjak Mateja14,Ko Albert Min-Shan1,Ding Manyu1215,Cao Peng12,Yang Ruowei12,Liu Feng12,Nickel Birgit13,Dai Qingyan12,Feng Xiaotian12,Zhang Lizhao12ORCID,Sun Chengkai16,Ning Chao17ORCID,Zeng Wen18,Zhao Yongsheng18,Zhang Ming1215,Gao Xing1215ORCID,Cui Yinqiu17ORCID,Reich David19202122ORCID,Stoneking Mark14,Fu Qiaomei1215ORCID

Affiliation:

1. Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences (CAS), Beijing 100044.

2. Center for Excellence in Life and Paleoenvironment, Chinese Academy of Sciences, Beijing 100044.

3. Department of Biology, University of Richmond, Richmond, VA 23173.

4. International Research Center for Austronesian Archaeology, Pingtan 350000.

5. Fujian Museum, Fuzhou 350001.

6. Shandong Provincial Institute of Cultural Relics and Archaeology, Jinan 250012.

7. Institute of History and Philology, Academia Sinica, Taipei 11529.

8. School of History and Culture, Shandong University, Jinan 250100.

9. Environment-Omics-Disease Research Center, China Medical University and Hospital, Taichung 40402.

10. Institute of Anthropology, National Tsinghua University, Hsinchu 30013.

11. School of Cultural Heritage, Northwest University, Xi’an 710069.

12. The Institute of Cultural Relics and Archaeology, Inner Mongolia Autonomous Region 010011.

13. School of Archaeology and Museology, Peking University, Beijing 100871.

14. Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, 04103 Leipzig.

15. University of Chinese Academy of Sciences, Beijing 100049.

16. Shandong Museum, Jinan 250014.

17. School of Life Sciences, Jilin University, Changchun 130023.

18. Institute of Cultural Heritage, Shandong University, Qingdao 266237.

19. Department of Genetics, Harvard Medical School, Boston, MA 02115.

20. Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138.

21. Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142.

22. Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115.

Abstract

A genetic history of China The history of human movements into and within China has been difficult to determine solely from archaeological investigations or genetic studies of contemporary peoples. Yang et al. sequenced DNA from 26 individuals from 9500 to 300 years ago from locations within China. Analyses of these individuals, along with previously sequenced ancient individuals and present-day genomes representing global populations, show a split between ancient humans in northern and southern China. Neolithic northern Chinese individuals are closest to modern-day East Asians, whereas ancient individuals from southern China are most closely related to modern-day Southeast Asians and show an affinity to modern-day Austronesian populations. These results indicate that there was a southward movement and admixture of peoples during the Neolithic that gave rise to modern-day populations in East Asia. Science this issue p. 282

Funder

Howard Hughes Medical Institute

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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