Classic Selective Sweeps Were Rare in Recent Human Evolution-Reference-Cited by-同舟云学术

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Classic Selective Sweeps Were Rare in Recent Human Evolution

Published:2011-02-18 Issue:6019 Volume:331 Page:920-924
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Hernandez Ryan D.¹,Kelley Joanna L.¹,Elyashiv Eyal²,Melton S. Cord¹,Auton Adam³,McVean Gilean³⁴,Sella Guy²,Przeworski Molly¹⁵⁶,

Affiliation:

1. Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

2. Department of Ecology, Evolution and Behavior, Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel.

3. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.

4. Department of Statistics, University of Oxford, Oxford OX1 3TG, UK.

5. Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA.

6. Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.

Abstract

Much human genetic variation is likely due to purifying selection against deleterious mutations.

Funder

National Institutes of Health

National Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Link

http://www.sciencemag.org/content/331/6019/920.full.pdf

Reference33 articles.

1. Positive Natural Selection in the Human Lineage

2. Constructing genomic maps of positive selection in humans: Where do we go from here?

3. The hitch-hiking effect of a favourable gene

4. The Signature of Positive Selection at Randomly Chosen Loci

5. Localizing Recent Adaptive Evolution in the Human Genome

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