Development of Monocytes, Macrophages, and Dendritic Cells

Author:

Geissmann Frederic1,Manz Markus G.2,Jung Steffen3,Sieweke Michael H.4,Merad Miriam5,Ley Klaus6

Affiliation:

1. Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection, and Inflammatory Diseases, King's College London, Great Maze Pond, London SE1 1UL, UK.

2. Division of Hematology, Department of Internal Medicine, Zürich University Hospital, CH-8091 Zürich, Switzerland.

3. Department of Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel.

4. Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix Marseille, Campus de Luminy, Case 906, 13288 Marseille Cedex 09, France; Institut National de la Santé et de la Recherche Médicale (INSERM), U631 Marseille, France; Centre National de la Recherche Scientifique (CNRS), UMR6102, Marseille, France.

5. Department of Gene and Cell Medicine and Institute for Immunology, Icahn Medical Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.

6. Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

Abstract

Development of Myeloid Immune Cells As leukocytes develop to maturity, they proceed through an array of phenotypically distinct intermediates. For T and B lymphocyte populations, the different developmental stages, anatomical locations, and cell signals required for progression are well established. However, until recently, much less has been known about how development proceeds in the myeloid lineage, which includes monocytes, macrophages, and dendritic cells. Geissmann et al. (p. 656 ) review our current understanding of myeloid lineage development and describe the developmental pathways and cues that drive differentiation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3