Affiliation:
1. Department of Virology, Erasmus Medical Center, 3015 GE Rotterdam, Netherlands.
Abstract
During the 2003 to 2004 outbreak of avian influenza A (H5N1) virus in Asia, there were anecdotal reports of fatal infection in domestic cats, although this species is considered resistant to influenza. We experimentally inoculated cats with H5N1 virus intratracheally and by feeding them virus-infected chickens. The cats excreted virus, developed severe diffuse alveolar damage, and transmitted virus to sentinel cats. These results show that domestic cats are at risk of disease or death from H5N1 virus, can be infected by horizontal transmission, and may play a role in the epidemiology of this virus.
Publisher
American Association for the Advancement of Science (AAAS)
Reference7 articles.
1. Are We Ready for Pandemic Influenza?
2. World Health Organization “Confirmed human cases of avian influenza A (H5N1) 7 September 2004 ” available at www.who.int/csr/disease/avian_influenza/country/cases_table_2004_09_07/en/print.html.
3. ProMED Mail “Avian influenza H5N1 mammals—East Asia” (Archive number 20040221.0560 21 February 2004) available at www.promedmail.org.
4. Replication of avian influenza A viruses in mammals
5. Pathogenesis of Influenza A (H5N1) Virus Infection in a Primate Model
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