1. The longest submitted sequence to date 1.492 Mb produced by the Olson laboratory at the University of Washington derives from the metabotropic glutamate receptor 8 gene on chromosome 7 (GenBank accession number ). Other sequences >1 Mb include the immunoglobulin λ locus (1.025 Mb accession numbers - and -); the T cell receptor α locus (1.071 Mb accession numbers -); the DiGeorge critical region (1.25 Mb ); and a region of chromosome 19q13 (1.02 Mb ). Numerous sequences in the several hundred kilobase range are now being produced by the large sequencing centers in the United States and elsewhere (for example the Sanger Centre Cambridge UK).
2. M. D. Adams et al. Nature 377 (suppl.) 3 (1995). EST databases can be accessed via the NCBI BLAST server ().
3. An STS-Based Map of the Human Genome
4. Cohen D., Chumakov I., Weissenbach J., Nature 366, 698 (1993).
5. Dib C., et al., ibid. 380, 152 (1996).