Transmission Dynamics and Control of Severe Acute Respiratory Syndrome

Author:

Lipsitch Marc12345,Cohen Ted12345,Cooper Ben12345,Robins James M.12345,Ma Stefan12345,James Lyn12345,Gopalakrishna Gowri12345,Chew Suok Kai12345,Tan Chorh Chuan12345,Samore Matthew H.12345,Fisman David12345,Murray Megan12345

Affiliation:

1. Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

2. Epidemiology and Disease Control Division, Ministry of Health, College of Medicine Building, 16 College Road, Singapore 169854.

3. Department of Medicine, University of Utah, Salt Lake City, UT 84132, USA.

4. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

5. City of Hamilton Public Health and Community Service Department, Hamilton, Ontario L8R 3L5, Canada.

Abstract

Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference23 articles.

1. Lancet 2003 361

2. See information from the World Health Organization (WHO) available online at www.who.int/csr/sarscountry/en/.

3. Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

4. J. S. M. Peiriset al., Lancet361, 1318 (2003).

5. A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

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