Ultrasound-Stimulated Vibro-Acoustic Spectrography

Author:

Fatemi Mostafa1,Greenleaf James F.1

Affiliation:

1. Ultrasound Research, Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

Abstract

An ultrasound method based on radiation force is presented for imaging the acoustic response of a material to mechanical excitation. Acoustic energy was emitted from solids and tissues in response to an oscillatory radiation force produced by interfering focused beams of ultrasound. Frequency spectra of ultrasound-stimulated acoustic emission exhibited object resonances. Raster-scanning the radiation force over the object and recording the amplitude and phase of the emitted sound resulted in data from which images related to the elastic compositions of the acoustically emitting objects could be computed. Acoustic emission signals distinguished tuning-fork resonances, submillimeter glass spheres, and calcification in excised arteries and detected object motions on the order of nanometers.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference15 articles.

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3. For a review of elasticity imaging methods, see Gao L., Parker K. J., Lerner R. M., Levinson S. F., Ultrasound Med. Biol. 22, 959 (1996).

4. The study of radiation force and radiation pressure dates back nearly one century, to the time of Rayleigh [Lord Rayleigh, Philos. Mag. 3, 338 (1902); ibid. 10, 364 (1905)]. More recent analysis of the theory and explanation of the physical significance of the mathematics can be found in G. R. Torr, Am. J. Phys. 52, 402 (1984) . Critical and historical reviews on radiation force and radiation pressure are presented in B-T. Chu, R. E. Apfel, J. Acoust. Soc. Am. 72, 1673 (1982) and R. E. Beyer, ibid 63, 1025 (1978) . Some recent analysis of radiation force and pressure in attenuating medium (which may be applicable to biological tissues) are presented in O. V. Rudenko, A. P. Sarvazyan, S. Y. Emelianov, J. Acoust. Soc. Am. 99, 2791 (1996) and Jiang Z.-Y., Greenleaf J. F., ibid 100, 741 (1996).

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