Population-level analysis of gut microbiome variation-Reference-Cited by-同舟云学术

Population-level analysis of gut microbiome variation

Published:2016-04-29 Issue:6285 Volume:352 Page:560-564
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Falony Gwen¹²,Joossens Marie¹²³,Vieira-Silva Sara¹²,Wang Jun¹²,Darzi Youssef¹²³,Faust Karoline¹²³,Kurilshikov Alexander⁴⁵,Bonder Marc Jan⁶,Valles-Colomer Mireia¹²,Vandeputte Doris¹²³,Tito Raul Y.¹²³,Chaffron Samuel¹²³,Rymenans Leen¹²³,Verspecht Chloë¹²,De Sutter Lise¹²³,Lima-Mendez Gipsi¹²,D’hoe Kevin¹²³,Jonckheere Karl²³,Homola Daniel²³,Garcia Roberto²³,Tigchelaar Ettje F.⁶⁷,Eeckhaudt Linda²³,Fu Jingyuan⁶⁸,Henckaerts Liesbet¹⁹,Zhernakova Alexandra⁶⁷,Wijmenga Cisca⁶,Raes Jeroen¹²³

Affiliation:

1. KU Leuven–University of Leuven, Department of Microbiology and Immunology, Leuven, Belgium.

2. VIB, Center for the Biology of Disease, Leuven, Belgium.

3. Vrije Universiteit Brussel, Faculty of Sciences and Bioengineering Sciences, Microbiology Unit, Brussels, Belgium.

4. Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.

5. Novosibirsk State University, Novosibirsk, Russia.

6. University of Groningen, University Medical Center Groningen, Department of Genetics, 9700 RB Groningen, Netherlands.

7. Top Institute Food and Nutrition, Wageningen, Netherlands.

8. University of Groningen, University Medical Center Groningen, Department of Pediatrics, 9700 RB Groningen, Netherlands.

9. KU Leuven–University Hospitals Leuven, Department of General Internal Medicine, Leuven, Belgium.

Abstract

“Normal” for the gut microbiota For the benefit of future clinical studies, it is critical to establish what constitutes a “normal” gut microbiome, if it exists at all. Through fecal samples and questionnaires, Falony et al. and Zhernakova et al. targeted general populations in Belgium and the Netherlands, respectively. Gut microbiota composition correlated with a range of factors including diet, use of medication, red blood cell counts, fecal chromogranin A, and stool consistency. The data give some hints for possible biomarkers of normal gut communities. Science , this issue pp. 560 and 565

Funder

Flemish government

Research Fund-Flanders (FWO)

King Baudouin Foundation

FP7 METACARDIS

VIB

Rega institute for Medical Research

KU Leuven

Agency for Innovation by Science and Technology (IWT)

Publisher

American Association for the Advancement of Science (AAAS)

Subject