Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication-Reference-Cited by-同舟云学术

Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication

Published:2005-12-09 Issue:5754 Volume:310 Page:1661-1665
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Goodman R. P.¹²,Schaap I. A. T.¹²,Tardin C. F.¹²,Erben C. M.¹²,Berry R. M.¹²,Schmidt C. F.¹²,Turberfield A. J.¹²

Affiliation:

1. Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK.

2. Department of Physics and Astronomy, de Boelelaan 1081, Vrije Universiteit, 1081 H Amsterdam, Netherlands.

Abstract

Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on a side, that can self-assemble in seconds with near-quantitative yield of one diastereomer. They can be connected by programmable DNA linkers. Their triangulated architecture confers structural stability; by compressing a DNA tetrahedron with an atomic force microscope, we have measured the axial compressibility of DNA and observed the buckling of the double helix under high loads.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference26 articles.

1. DNA in a material world

2. Commercial oligonucleotide synthesis costs ∼50¢ per base for several nanomoles and at its simplest fabrication requires only mixing of aqueous solutions.

3. Design and self-assembly of two-dimensional DNA crystals

4. J. Malo et al., Angew. Chem. Int. Ed.44, 3057 (2005).

5. DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires

Cited by 989 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The combination of DNA nanostructures and materials for highly sensitive electrochemical detection;Bioelectrochemistry;2024-06

2. Crab-shaped DNA tetrahedral nanomachine for silencing undruggable mRNA targets in prostate cancer;Nano Today;2024-04

3. DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules;Bioactive Materials;2024-03

4. Radiolabeled Tracing Techniques Illuminating Blood Pharmacokinetics in Nanomedicine;Nano Biomedicine and Engineering;2024-03

5. Tetrahedral DNA frameworks for biosensing and imaging analysis in living cells;Nano Today;2024-02