Influence of Synaptic Vesicle Position on Release Probability and Exocytotic Fusion Mode-Reference-Cited by-同舟云学术

Influence of Synaptic Vesicle Position on Release Probability and Exocytotic Fusion Mode

Published:2012-03-16 Issue:6074 Volume:335 Page:1362-1366
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Park Hyokeun¹,Li Yulong¹,Tsien Richard W.¹²

Affiliation:

1. Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.

2. NYU Neuroscience Institute and Department of Physiology and Neuroscience, New York University, New York, NY 10016, USA.

Abstract

A Synaptic Vesicle in Time Synaptic vesicles move extensively within presynaptic nerve terminals, and their positional features are thought to have an impact on the likelihood and mode of vesicle fusion and transmitter release. Park et al. (p. 1362 , published online 16 February) now provide real-time, three-dimensional tracking of individual synaptic vesicles in living nerve terminals. Single synaptic vesicles were identified within hippocampal neurons right up to the moment of exocytosis.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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