Case Report: Chorea an unusual presentation of a patient with clinically isolated syndrome (multiple sclerosis)

Abstract

This is a case report of a 26 year old girl who presented with choreiform movements of the upper and lower limbs and generalised tonic clonic seizures who had an entity called clinically isolated syndrome of multiple sclerosis on investigation. The pooled incidence rate in 75 reporting countries was 2.1 per 100,000 persons/year, with 32 years of age being the mean age of diagnosis. But multiple sclerosis is a white matter disease and choreiform movements are due to involvement of the grey matter of the brain. There have only been a few case reports of patients with multiple sclerosis having choreoathetoid movements reported.