Prevalence and risk factors of deep venous thrombosis of hospitalizations in plateau: A cross-section analysis

Author:

Sun Lijuan1,Pan Shiqin1,Li Yuemei1,Luo Mingqin1,Li Xiaofang1,Ma Hongmei1,Zhang Jingni1,Wang Limei2,Yong Cuo3

Affiliation:

1. Qinghai Provincial People’s Hospital

2. The Third People's Hospital of Xining

3. Yushu People's Hospital

Abstract

Abstract Background: To elucidate the prevalence of and associated risk factors for deep venous thrombosis (DVT) in hospitalized patients in plateau areas. Methods: We enrolled patients who were hospitalized in three grade III-a hospitals in Qinghai Province, China, between January 2020 and October 2020. The demographic and clinical data and laboratory results were collected at admission. Simultaneously, we performed ultrasonography of the bilateral lower extremities, and the length of hospital stay was collected before discharge. Results: In total, 3432 patients were enrolled; of them, 159 were diagnosed with DVT (4.60%). The total length of hospital stay of patients with DVT was longer than that of those without DVT (16.40 ± 7.66 vs. 14.77 ± 8.55 days). Age of >50 years (OR = 1.969, 95% CI: 1.192–3.252, P = 0.008), residence altitude of ≥3000 m (OR = 2.344, 95% CI: 1.238–4.438, P = 0.009), D-dimer level of ≥0.5 mg/L (OR = 2.53, 95% CI: 1.813–3.529, P < 0.001), comorbidities (OR = 1.906, 95% CI: 1.365–2.662, P < 0.001),history of varicose veins (OR = 2.202, 95% CI: 1.096–4.425, P = 0.027), and current medications (OR = 2.591, 95% CI: 1.857–3.616, P < 0.001) were identified as risk factors for DVT in plateau areas. Conclusion: The prevalence of DVT in hospitalized patients in plateau areas was 4.60%. We recommend considering individualized risk stratification (age > 50 years, residence altitude ≥ 3000 m, history of varicose veins, D-dimer level ≥ 0.5 mg/L, current medications, and comorbidities) for patients at admission.

Publisher

Research Square Platform LLC

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