Characteristics and survival of multifocal/multicentric breast cancer: a retrospective study of 415 cases

Author:

Tong Ying1,Zhang Chuanpeng1,Yang Susu1,Liu Yitao1,Sun Feixiang1,Yu Ziyi2,Fu Ziyi2,Zhao Yi2

Affiliation:

1. Nanjing Medical University

2. The First Affiliated Hospital of Nanjing Medical University

Abstract

Abstract Objectives: This study was to compare the clinicopathological and prognostic characteristics of multifocal/multicentric (MF/MC) with unifocal (UF) breast cancer to study the determinants of cancer multiplicity in survival. Methods: A retrospective analysis of 83 MF/MC and 332 UF breast cancer patients was conducted. Clinicopathological characteristics and prognostic indicators were compared. Results: MF/MC breast cancer were more likely to have lymph node metastasis and lymph vascular/perineural invasion. There was a statistically significant difference in the LRFS rate. Cancer multiplicity was not an independent prognostic factor. Conclusion: MF/MC breast cancer are more aggressive. However, cancer multiplicity did not affect prognosis.

Publisher

Research Square Platform LLC

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