Affiliation:
1. Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine
Abstract
Abstract
Objectives
Early-stage esophageal cancer is treated using endoscopic submucosal dissection and esophagectomy. Field cancerization in patients with early-stage esophageal cancer affects treatment outcomes and causes synchronous or metachronous head and neck cancers. We hypothesized that esophagectomy could provide better overall and recurrence-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer.
Methods
We retrospectively identified patients with early esophageal squamous cell carcinoma and synchronous or metachronous head and neck cancers. We separated the patients into endoscopic submucosal dissection and esophagectomy groups to compare overall and recurrence-free survivals.
Results
The study included 106 patients, 25 of whom underwent endoscopic submucosal dissection and 81 underwent esophagectomy. Overall and recurrence-free survivals did not show significant differences between the two groups for both synchronous and metachronous head and neck cancers.
Conclusions
Endoscopic submucosal dissection could provide similar overall and recurrence-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer.
Publisher
Research Square Platform LLC