COVID-19 in a Child with Primary Specific Antibody Deficiency

Author:

Ahanchian Hamid1,Moazzen Nasrin1,Faroughi Majid Sezavar Dokht2,Khalighi Negar1,Khoshkhui Maryam1,Aelami Mohammad Hassan3,Haghi Nasrin Sadat Motevalli1,Rezaei Nima4

Affiliation:

1. Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2. Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3. Department of Pediatrics and Hand Hygiene and Infection Control Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

4. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Abstract Background. In the recent coronavirus disease 2019 (COVID-19) pandemic, millions of people have been affected so far. Clinical manifestations and natural history of infections have a very wide range, which is important to know it in various underlying diseases. Although children are less affected than adults, its presentation especially in those with underlying diseases should not be neglected.Case presentation. Herein we report the first case of specific antibody deficiency, who was affected with COVID-19. The patient suffered from rhinorrhea and modestly increased in productive cough, but real-time reverse transcription polymerase chain reaction was positive for COVID-19.Conclusions. Although presentation of COVID-19 in patients with immunodeficiency could be mild, it should not be missed, while early diagnosis and appropriate treatment can survive affected patients.

Publisher

Research Square Platform LLC

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