A case of primary orbital lymphoma manifested as increased intraocular pressure

Abstract

Abstract Background Orbital lymphoma may occur with or without systemic symptoms. Lymphoma can influence any different soft tissue structure in the orbital cavity except the orbital bone, and exhibit similar clinical and imaging features to other orbital diseases, so it is often misdiagnosed. The pathogenesis of lymphoma is closely related to the prognosis. Early diagnosis of the disease is beneficial to the definition and treatment of the disease, and can increase the survival time of the patient. Case presentation: An elderly man presented to local hospital with sudden eyelid swelling and vision loss in his left eye. During the follow-up treatment, the intraocular pressure of the patient's left eye increased gradually and the visual acuity gradually decreased to no light perception. We performed CT-guided puncture of the orbital mass. The pathological findings suggested small cell malignancy. Combined with the clinical manifestations and signs, the patient was considered to be ocular non-Hodgkin diffuse large B-cell lymphoma. Then the patient was given combined chemotherapy and radiotherapy. After the treatment, the patient's eye swelling and pain were significantly improved. Conclusions To the best of our knowledge, this is one of the few described cases of orbital lymphomas that begin with increased intraocular pressure.