Investigating the clinical course of patients with covid-19 and its relationship with receiving the vaccines administered at the COVID-19 center of Sabzevar University of Medical Sciences

Abstract

Abstract Background Assessing and following up the clinical status of patients with COVID-19 can provide useful information for developing treatment algorithms to clarify treatment recommendations and improve patients’ stability after discharge. This study aimed to address the clinical course of patients with COVID-19 and its relationship with administration of recommended vaccines. Methods This cross-sectional study focused on 140 patients with COVID-19, selected based on convenience sampling, who were discharged from Vasei Hospital affiliated with Sabzevar University of Medical Sciences in between February 2022 and July 2022. Using a questionnaire, we assessed the recovery process and clinical course of patients 4 and 12 weeks after discharge. The data were analyzed in SPSS v. 24 at the significance level of 5%. Results Administration of the recommended vaccine doses and the recovery rate had a significant relationship in the second follow-up (P = 0.026), but not in the first follow-up. There was a significant relationship between the results of the PCR test in second period and the recovery rate in the first follow-up (P = 0.002), but there was no such significant relationship in the second follow-up (P = 0.51). Conclusion The results of this study showed that vaccination affects the level of immunity and the long-term recovery of patients with COVID-19.