Prevalence and risk factors for dementia and mild cognitive impairment among older people in Southeast China: a community-based study

Author:

Jiang Bin1,Liu Qi1,Li Jian-Peng1,Lin Si-Ning1,Wan Hui-Juan1,Yu Zi-Wen1,Wang Jing1,Zhuang Wei2,Tang Jia-Hui1,Chen Cai-Hong1,Li Fa-Yin1,Bi Min1,Xiao Nai-An3,Zheng Kun-Mu1

Affiliation:

1. The First Affiliated Hospital of Xiamen University, Xiamen University

2. Nanjing County Hospital

3. The Third Hospital of Xiamen

Abstract

Abstract Background As the aging population grows, there is a rapid increase in the number of individuals with dementia in China. We aimed to conduct a community-based study on the prevalence and risk factors for dementia and mild cognitive impairment (MCI) among older adults in China. Methods In this study, 20070 individuals aged ≥ 65 were recruited between January 1st, 2022, and February 1st, 2023, from ten communities in Xiamen City, China. We collected data on age, sex, level of education, and medical history, as well as global cognition and functional status. The prevalence of dementia and MCI was examined, and the risk factors for the different groups were assessed. Results The overall prevalence of dementia and MCI was approximately 5.4% (95% confidence interval [CI], 5.1–5.7) and 7.7% (95% CI, 7.4–8.1), respectively. The results also indicated that dementia and MCI share similar risk factors, including older age, female sex, hypertension, and diabetes mellitus. Compared to individuals with no formal education, those with > 6 years of education had an odds ratio for MCI of 1.93 (95% CI, 1.57–2.38). We also found that only 5.5% of the positive participants chose to be referred to the hospital for further diagnosis and treatment during follow-up visits. Conclusions We estimated the prevalence and risk factors of dementia and MCI among individuals aged 65 years or older in Southeast China. These findings are crucial for preventing and managing dementia and MCI in China.

Publisher

Research Square Platform LLC

Reference31 articles.

1. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019;Collaborators GBDDF;Lancet Public Health,2022

2. The cost of Alzheimer's disease in China and re-estimation of costs worldwide;Jia J;Alzheimers Dement,2018

3. Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease;Prestia A;Neurology,2013

4. Prevention of dementia in an ageing world: Evidence and biological rationale;Grande G;Ageing Res Rev,2020

5. Multi-domain interventions for the prevention of dementia and cognitive decline;Hafdi M;Cochrane Database Syst Rev,2021

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3