Risk Prediction of Second Primary Malignancies in Patients after Rectal Cancer: Analysis Based on SEER Program

Author:

Sun Yong-Chao1,Zhao Zi-Dan1,Fu Yue2,Jiao Yu-Wen2,Zhang Jia-Wen2,Shi Wei-Hai2

Affiliation:

1. Bengbu Medical College

2. Changzhou No.2 People's Hospital

Abstract

Abstract Background This study will focus on exploring the clinical characteristics of rectal cancer (RC) patients with SPMs and constructing a prognostic nomogram to provide clinical treatment decisions.Methods We determined the association between risk factors and overall survival (OS) while establishing a nomogram to forecast the further OS status of these patients via Cox regression analysis. Finally, we evaluated the performance of the prognostic nomogram to predict further OS status.Results Nine parameters were identified to establish the prognostic nomogram in this study, and, the C-index of the training set and validation set was 0.691 (95%CI, 0.662–0.720) and 0.731 (95%CI, 0.676–0.786), respectively.Conclusions We systematically explored the clinical characteristics of SPMs after RC and constructed a satisfactory nomogram.

Publisher

Research Square Platform LLC

Reference31 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray F;CA Cancer J Clin,2018

2. Sung H, Ferlay J, Siegel RL et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 71(3), 209–249 (2021).

3. Global patterns and trends in colorectal cancer incidence and mortality;Arnold M;Gut,2017

4. Impact of Treatment Coordination on Overall Survival in Rectal Cancer;Biju K;Clin Colorectal Cancer,2021

5. Cancer statistics, 2020;Siegel RL;CA Cancer J Clin,2020

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3