Comparison of pregnancy outcomes in two methods of frozen and fresh embryo transfer in infertile women with endometriosis

Abstract

Abstract Introduction: infertility is one of the most important complications in patients with endometriosis however, the use of assisted reproductive treatments have resulted in successful fertility and childbearing in a significant proportion of patients. In this study the outcome of pregnancy was compared between two methods of frozen and fresh embryo transfer in infertile women with endometriosis who underwent assisted reproductive treatment in Shariati Hospital from 2013 to 2020. Methods: From 197 patients with endometriosis who received infertility treatment, 105 were assigned to fresh embryo transfer group and 92 were assigned to frozen embryo transfer group. Patient’s data was gathered using archive files. Patients in both groups were matched in terms of age, BMI (Body Mass Index), duration of primary infertility, base FSH (Follicle-Stimulating Hormone) serum levels and number of transferred embryos (P>0.05). The IVF (In Vitro Fertilization) pregnancy outcomes in two groups were compared in terms of live birth rate, clinical pregnancy rate, chemical pregnancy rate, miscarriage rate, ongoing pregnancy rate. Results: Live birth rate, clinical pregnancy rate, ongoing pregnancy rate and chemical pregnancy rate in frozen embryo transfer group was significantly higher than fresh embryo transfer group (P<0.049). miscarriage rate was not significantly different in both groups (P=0.546). Conclusion: According to the results and parameters in this study frozen embryo transfer is more successful in terms of pregnancy outcomes than fresh embryo transfer.