Association between serum Calcium and 28-day mortality in Pediatric Pneumonia: Insights from a PICU Retrospective Cohort-Reference-Cited by-同舟云学术

Association between serum Calcium and 28-day mortality in Pediatric Pneumonia: Insights from a PICU Retrospective Cohort

Published:2024-02-01 Issue: Volume: Page:
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Author:

Zhao Jinling¹,Liu Meihong²,Yu Dan³,Zhang Ying-ying³

Affiliation:

1. Affiliated Hospital of Jiangnan University

2. Shaanxi Provincial People's Hospital

3. Affiliated Wuxi Fifth Hospital of Jiangnan University

Abstract

Abstract This study investigates the impact of serum calcium levels on the 28-day hospital mortality rate in children with pneumonia, a topic not extensively explored previously. Analyzing data from 414 patients at Zhejiang University Medical College's Children's Hospital (2010–2019), the study categorized patients by serum calcium levels for 28-day mortality monitoring. Results show that each 1mmol/dL increase in serum calcium reduced 28-day mortality risk by 26% (HR: 0.74, 95% CI: 0.65–0.85). Patients with higher serum calcium levels had a 63% lower mortality rate compared to those with lower levels (HR: 0.37, 95% CI: 0.16–0.85). These findings, consistent across various subgroups, highlight serum calcium as a significant prognostic marker for pediatric pneumonia, influencing clinical decisions and pointing to the need for further research in this area.

Publisher

Research Square Platform LLC

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