Comparative Visual Performance of Ultraviolet Light-Filtering and Violet Light-Filtering Monofocal Intraocular Lenses of the Same Material and Basic Design

Abstract

Abstract We compared the visual performance of ultraviolet light-filtering (ZCB00, Johnson & Johnson Surgical Vision) and violet light-filtering (ZCB00V, same manufacturer) monofocal intraocular lenses (IOLs) of the same material and basic design 10 weeks after the last surgery for implantation with bilateral lenses implanted ≤ 3 months apart in cataract patients treated between 2011 and 2020. The ZCB00 and ZCB00V groups comprised 904 eyes of 452 patients (72.3 ± 6.8 years; females/males, 268/184) and 1374 eyes of 687 patients (73.0 ± 7.4 years; female/male, 415/272), respectively. A linear mixed-effects model using the binocular data, with strict adjustments for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations, and pupil diameter, ensured statistical validity. Uncorrected intermediate/near visual acuity, corrected near visual acuity, and certain 25-item Visual Function Questionnaire (VFQ-25) components (Role_Limitation, Mental_Health, Social_Function, Distance_Vision, Color_Vision) were slightly but significantly better in ZCB00 recipients (p < 0.05, Wald). In contrast, ZCB00V recipients had significantly better contrast sensitivity with glare (visual angle of target: 6.3°/4.0°/0.7°; p < 0.00068, Wald), slightly but significantly better contrast sensitivity without (4.0°/2.5°/1.6°) and with glare (2.5°/1.6°/1.0°), VFQ-25 General_Health scores, and near spectacle independence, and slightly but significantly smaller higher-order aberrations (internal, scaled to a 6-mm pupil; Wavefront_6_post_I_Trefoil) (p < 0.05, Wald).