Clinical study of tear total IgE detection in the diagnosis and treatment of allergic conjunctivitis in children

Author:

Guan Yingjie1,Xu Wenfei1,Liao Yan1,Cao Jinting1,Chen Kejing1,Lin Yan1,Huang Jing2

Affiliation:

1. Guangzhou Medical University

2. Guangzhou Women and Children’s Medical Center

Abstract

Abstract

Objective To provide a new method for the diagnosis of allergic conjunctivitis by detecting the total IgE level of tears in children. Methods 40 patients in our hospital were studied. By measuring and comparing the total IgE level of tears in the experimental group and the control group, the difference between the two groups was compared by statistical methods. Results A total of 40 cases were collected, including 26 cases in the AC exper- imental group and 14 cases in the control group. The total IgE concentration in tears of allergic conjunctivitis patients in the experimental group was mostly lower. There was no significant difference in total IgE level between the control group and the experimental group. Conclusion Tear detection has guiding significance for the diagnosis of AC, but it is difficult to reflect in children. Further studies should be conducted on the basis of this study to make tear detection more accurate and effective for the diagnosis and treatment of allergic conjunctivitis in children.

Publisher

Springer Science and Business Media LLC

Reference15 articles.

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3. Prevalence of allergic sensitization with vernal keratoconjunctivitis: A systematic review with meta-analyses;Rasmussen M;ACTA OPHTHALMOL,2023

4. Zhou L, Liu B. Paying attention to proteomics of human tear: clinical significance and application in ocular surface diseases. 2016.

5. Multiple cytokines in human tear specimens in seasonal and chronic allergic eye disease and in conjunctival fibroblast cultures;Leonardi A;CLIN EXP ALLERGY,2006

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