Unresectable Leiomyosarcoma Of The Inferior Vena Cava With Right Atrium Tumor Thrombus: When To Deem This Tumor Inoperable? A Case Report And Literature Review.-Reference-Cited by-同舟云学术

Unresectable Leiomyosarcoma Of The Inferior Vena Cava With Right Atrium Tumor Thrombus: When To Deem This Tumor Inoperable? A Case Report And Literature Review.

Published:2023-09-28 Issue: Volume: Page:
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Author:

Castellanos Luis D.¹,Tabbara Marina M.²,Livingstone Alan S.²,Salerno Tomas A.²,Gonzalez Javier³,Ciancio Gaetano²

Affiliation:

1. Universidad del Zulia, School of Medicine

2. University of Miami Miller School of Medicine, Jackson Memorial Hospital

3. Hospital General Universitario Gregorio Marañón

Abstract

Abstract Background Leiomyosarcomas (LMS) of the inferior vena cava (IVC) are a rare form of retroperitoneal malignancy and their venous extension to the right atrium is an even rarer event. These tumors pose a unique surgical challenge and often require a multidisciplinary team-based approach for their surgical treatment. Case presentation: We present a case of a 68-year-old male with primary LMS of the IVC with a tumor thrombus extending into the right atrium that was initially deemed inoperable. Conclusions After extensive neoadjuvant chemo-radiation with minimal tumor effect, the patient underwent en-bloc surgical resection of the tumor along with removal of the infrarenal IVC and right kidney and adrenal without the need for cardiopulmonary bypass.

Publisher

Research Square Platform LLC

Reference34 articles.

1. Gafarli S, Igna D, Wagner M, Nistor A, Glanemann M, Stange B. Dyspnea due to an uncommon vascular tumor: leiomyosarcoma of the infrahepatic vena cava inferior. Surg Case Rep [Internet]. 2020 Jun 16 [cited 2023 Aug 30];6:136. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297879/

2. Jain S, Xu R, Prieto VG, Lee P. Molecular classification of soft tissue sarcomas and its clinical applications. Int J Clin Exp Pathol [Internet]. 2010 Apr 23 [cited 2023 Aug 30];3(4):416–29. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872748/

3. Saltus CW, Calingaert B, Candrilli S, Lorenzo M, D’yachkova Y, Otto T, et al. Epidemiology of Adult Soft-Tissue Sarcomas in Germany. Sarcoma [Internet]. 2018 Apr 4 [cited 2023 Aug 30];2018:5671926. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904765/

4. Surgical treatment and outcomes of patients with primary inferior vena cava leiomyosarcoma;Hollenbeck ST;J Am Coll Surg,2003

5. Perl L, Virchow R. Ein Fall von Sarkom der Vena cava inferior. Arch Für Pathol Anat Physiol Für Klin Med [Internet]. 1871 Aug 1 [cited 2023 Aug 30];53(4):378–83. Available from: https://doi.org/10.1007/BF01957198