Carbohydrate intake and diabetic drugs: Understanding the dynamic interplay in diabetes management

Abstract

Abstract The body relies on carbohydrate as its main source of energy to carry out daily activities. Measuring carbohydrate allows patients to estimate the amount of carbohydrates in meals and snacks, and they can then alter their prescription as necessary. A thorough grasp of how medication therapy and carbohydrate intake interact is necessary for effective diabetic control. This systematic review attempts to summarise the most recent data on the influence of drug and carbohydrate interaction on glycaemic control in patients because there is currently no clear outline of the drug and carbohydrate interaction. Electronic databases such as PubMed, Embase, Google Scholar, and Scopus were used to conduct a thorough literature search. Included were studies examining the relationship between dietary carbohydrate intake and particular diabetes medications. In accordance with the eligibility requirements, data extraction and quality evaluation were done. Data reporting adhered to PRISMA. The systematic review included a total of 55 studies that satisfied the inclusion requirements. The studies included quantitative, qualitative and mixed method studies. The outcomes of glycaemic control, including fasting blood glucose, postprandial glucose levels, and HbA1c, were significantly influenced by the interaction between medication therapy and carbohydrate intake, according to the data. This systematic review emphasises the significance of taking into account how medication therapy and carbohydrate intake interact while managing diabetes. The results highlight the need for tailored strategies to improve glycaemic control while reducing unfavourable outcomes. To clarify the mechanisms behind these interactions and create evidence-based recommendations for customised diabetes therapy, more investigation is required.