Simultaneous adsorption of Amoxicillin and Cefixime by facile synthesized Chitosan@Polyacrylamide@ZIF-8; Isotherm and Kinetic study

Abstract

Abstract In recent years, drug use around the world due to population growth and the spread of disease is increasing these include antibiotics which account for about 10 to 15% of drug use. The studies show that antibiotics have a permanent and destructive effect on the environment which not completely removed in refineries. In this study, the Chitosan@Polyacrylamide@ZIF-8 as an adsorbent was simultaneously used to removal of Cefixime and Amoxicillin from the aqueous solution by adsorption method. XRD and FTIR patterns were analyzed for investigation of the surface crystallinity and the chemical properties of the adsorbent. In the following, SEM and TEM images were used for surface morphology study. Finally, a numerical investigation have been done for predicting the adsorption effective parameters. The results show that pH 4, contact time 30 minutes, initial concentration 50 mg/L, temperature 25° C and 15 mg of adsorbent are optimal condition which removal percentage achieved up to %90. The Langmuir, Friendlich, Tamkin, and Dubinin-Radushkovich isotherms were examined by experimental data and Langmuir model presented the best consistency with the experimental results and the maximum calculated adsorption capacity for Amoxicillin and Cefixime are 910 mg/g and 588 mg/g, respectively. Pseudo-first order, Pseudo-second order and intra-particle diffusion were investigated for kinetic studies. The results of the calculations illustrated the Pseudo second order model has been dominant. Overall, this study expresses, Chitosan@Polyacrylamide coated by ZIF-8 can be used an appropriate, effective and economical adsorbent for the adsorption of Amoxicillin and Cefixime.