Affiliation:
1. NASA Ames Research Center
2. NASA
3. Blue Marble Space
4. KBR, NASA Ames Research Center
5. NASA/WyLe Labs
6. Weill Cornell Medicine
Abstract
Abstract
The increasing accessibility of commercial and private space travel necessitates a profound understanding of its impact on human health. The NASA Open Science Data Repository (OSDR) provides transparent and FAIR access to biological studies, notably the SpaceX Inspiration4 (I4) mission, which amassed extensive data from civilian astronauts. This dataset encompasses omics and clinical assays, facilitating comprehensive research on space-induced biological responses. These data allow for multi-modal, longitudinal assessments, bridging the gap between human and model organism studies. Crucially, community-driven data standards established by NASA's OSDR Analysis Working Groups empower artificial intelligence and machine learning to glean invaluable insights, guiding future mission planning and health risk mitigation. This article presents a concise guide to access and analyze I4 data in OSDR, including programmatic access through GLOpenAPI. This pioneering effort establishes a precedent for post-mission health monitoring programs within space agencies, propelling research in the burgeoning field of commercial space travel's impact on human physiology.
Publisher
Research Square Platform LLC
Reference11 articles.
1. NASA GeneLab: interfaces for the exploration of space omics data;Berrios DC;Nucleic Acids Res,2021
2. Advancing the Integration of Biosciences Data Sharing to Further Enable Space Exploration;Scott RT;Cell Rep,2020
3. GeneLab: Omics database for spaceflight experiments;Ray S;Bioinformatics,2019
4. Berrios, D.C., A. Beheshti, and S.V. Costes, FAIRness and Usability for Open-access Omics Data Systems. AMIA Annu Symp Proc, 2018. 2018: p. 232–241.
5. linkedISA: semantic representation of ISA-Tab experimental metadata;González-Beltrán A;BMC Bioinformatics,2014