Effect of Ozone and Low Power Laser as Therapeutic Alternatives on the Alveolar Repair Process After Tooth Extraction in Rats Wistar Exposed to Nicotine

Abstract

Abstract The aim of this study was to evaluate the alveolar repair process in rats exposed to nicotine after tooth extraction, using ozonised water and low-power laser therapy (LPLT) as therapeutic adjuvants. Thirty Wistar rats (Rattus Norvegicus) were used and given the nicotine solution via subcutaneous tissue. After 7 days, the upper right central incisor was surgically extracted. Three days after the surgical procedure, the animals continued to receive nicotine until the day of euthanasia, totalling 21 days after extraction. The result was that the groups that received coadjuvant therapy had neoformed mature bone, unlike the group that did not receive it. Based on the literature and the results obtained, we can conclude that nicotine negatively influenced the healing process and bone repair in the alveoli; however, the use of ozonised water and LPLT, even in the presence of nicotine, was effective, as it enhanced the repair process, making them good options for surgical procedures in patients who smoke.