Diagnostic Value of Hyperbilirubinemia and Basic Laboratory Tests in Simple and Complicated Appendicitis

Abstract

Abstract Purpose We aimed to investigate the effectiveness of total serum bilirubin and basic laboratory tests (white blood cell (WBC), C-reactive protein (CRP), Neutrophile Lymphocyte ratio (NLR), Platelet count, Platelet Lymphocyte ratio (PLR), Mean Platelet Volume (MPV), Platelet Distribution Width (PDW)) preoperatively in determining the severity of AA in patients operated for AA and reported as AA (complicated-simple) as a result of pathology.Method The medical records of over the age of 18 who underwent appendectomy with the diagnosis of AA between January 2015 and December 2019 in the General Surgery Clinic of Harran University Faculty of Medicine were evaluated retrospectively. The patients were divided into two groups based on the pathology result as simple or complicated appendicitis. Demographic characteristics of all patients, preoperative laboratory tests values were evaluated.Results The mean age of 386 patients included in the study was 35.3 (18–88) years. Based on the pathology result, 296 (76.7%) patients were evaluated as simple; 90 (23.3%) patients were evaluated as complicated AA. According to the pathology result, the mean age of the complicated patients (p = 0.001), the mean length of hospital stay (p < 0.001), the mean NLR (p = 0.008), the mean PLR (p = 0.036), the mean total bilirubin (p = 0.002), and the mean preoperative CRP (p < 0.001) were significantly higher.Conclusion Although total bilirubin and CRP appear to be the most important diagnostic parameters in the differentiation of simple and complicated appendicitis in the preoperative period, no single parameter with high specificity has been detected.