The Significance of Filling Ultrasonography for Preoperative Staging of Colon Cancer Diagnosis: A Prospective Study

Abstract

Abstract Purpose To investigate the value of filling ultrasonography in the preoperative staging diagnosis of colon cancer. Methods This study was a prospective, single-center, observational study. We performed CT examination and filling ultrasonography in 118 patients diagnosed with colon cancer by preoperative pathologic biopsy and compared the accuracy of filling ultrasonography and CT examination and the combination of the two examinations in the diagnosis of preoperative staging of colon cancer, using postoperative pathologic findings as the gold standard. Results In 118 patients, the overall diagnostic compliance rate of ultrasonography for T stage of colon cancer was 69.5% (86/118), of which the diagnostic compliance rate for T1-T2 stage, 75% (63/84) for T3 stage, and 63.6% (14/22) for T4 stage. the overall diagnostic compliance rate for lymph node metastasis of colon cancer was 68.6% (81/118), of which the diagnostic compliance rate for N0 was 81.7% (49/60), N1 59.6% (28/47), and N2 36.4% (4/11).The total diagnostic compliance rate of CT for the T-stage of colon cancer was 55.9% (68/118), of which the diagnostic compliance rate for the T1-T2 stage was 33.3% (4/12), 52.38% (44/84) for T3 stage and 90.9% (20/22) for T4 stage; the total diagnostic compliance rate of CT for lymph node metastasis of colon cancer was 39.8% (47/118), of which the diagnostic compliance rate was 28.3% (17/60) for N0, 44.6% (21/47) for N1 and 81.8% (9/11) for N2. By ROC analysis, ultrasonography was superior to CT for the diagnosis of T-stage (0.438 vs 0.243, P < 0.05) and N-stage (0.480 vs 0.231, P < 0.005). Conclusion Filling Ultrasound is valuable in the diagnosis of tumor characterization, localization, and preoperative staging, and the combined diagnosis with CT significantly improves the accuracy of colon cancer diagnosis and makes up for the shortcomings of the examination.