Ochrobactrum anthropi infection following corneal transplantation -A Case Report and Review of Literature

Abstract

Abstract Background Ochrobactrum anthropi is widely distributed and primarily infects patients with compromised immune functions .Although historically considered to possess low toxicity and pathogenicity, Ochrobactrum anthropi can lead to severe purulent infection. Here, we present a case of Ochrobactrum anthropi infection following corneal transplantation surgery,examining the occurrence and outcome of such infections post-transplantation. Case presentation: A retrospective analysis of cases involved examinations, genetic testing for diagnosis, and subsequent treatment. Patients with fungal corneal ulcer perforation, undergoing partial penetrating keratoplasty, exhibited anterior chamber exudation and purulence post-surgery. Despite unsuccessful antifungal treatment, genetic testing of anterior chamber fluid and purulent material confirmed Ochrobactrum anthropi infection. Antimicrobial treatment specifically targeting Ochrobactrum anthropi proved efficacious. Conclusion Inflammatory reactions following corneal transplantation should be vigilant for multiple infections. Genetic testing of aqueous humor holds significant guiding implications for clinical diagnosis and treatment.