Evaluation of Isotretinoin effects on depression, sleep apnea and sleep quality-Reference-Cited by-同舟云学术

Evaluation of Isotretinoin effects on depression, sleep apnea and sleep quality

Published:2023-09-05 Issue: Volume: Page:
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Author:

Orenay Ozge Mine¹,Temel Berkay¹,Capci Arcan Kivanc¹,Bal Zulal Inci¹,Karaosmanoglu Nermin¹

Affiliation:

1. Ankara Training and Research Hospital

Abstract

Abstract Background Isotretinoin is used to treat severe acne, treatment-resistant moderate acne and acne that leads to scarring or psychological distress. It has many side effects and is also associated with depression, sleep apnea and sleep disturbances. Objectives In this study, we aimed to evaluate the effects of isotretinoin on depression, sleep apnea and sleep quality. Methods A total of 42 patients diagnosed with acne and started isotretinoin treatment were included in the study. At baseline and after three months of treatment, patients filled out a questionnaire containing the Beck Depression Inventory (BDI), the Berlin Questionnaire (BQ) and the Pittsburg Sleep Quality Index (PSQI) in order to compare the effects of isotretinoin. Results There was no statistically significant difference in BDI, BQ and PSQI scores between week 0 and week 12 of treatment (p = 0.53, p = 0.5, p = 0.035). Conclusion This study showed no association between the use of isotretinoin and depression and sleep quality.

Publisher

Research Square Platform LLC

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