“Microwave-Assisted, Solvent Free, One Pot Synthesis of Novel Bioactive Imidazolyl - Pyrazole derivatives catalyzed by Mesolite type Natural Zeolite”

Author:

Dhotre Sandip1,Pawar Ganesh2,Pawar Rajendra3,Vaidya Sayujjata1

Affiliation:

1. Vivekanand Arts, Sardar Dalipsingh Commerce and Science College, Aurangabad-431001.

2. University Department of Basic and Applied Science (Chemistry) MGM University Aurangabad-431001.

3. Department of Chemistry, Shivchhatrapati college, Aurangabad-431005

Abstract

Abstract Novel Imidazolyl-Pyrazole derivatives have been synthesized by cyclocondensation of 1, 3-diphenyl pyrazole-4-carbaldehyde, benzil, and substituted aniline and ammonium acetate by using mesolite type natural zeolite as an efficient and heterogenous catalyst under microwave condition. The synthesised novel Imidazolyl-Pyrazole derivatives are fully characterized by FT-IR, 1H-NMR, 13C-NMR and LC-MS techniques. The synthesized Imidazolyl-Pyrazole derivatives were screened for anti-bacterial and anti-fungal activities and compared with standard drug molecules.

Publisher

Research Square Platform LLC

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